Florian Raible studied Molecular Biology and Biochemistry in Heidelberg. After work on epigenetic regulation (Polycomb Repressive Complexes; MGH, Boston) and vertebrate brain patterning (MPI-CBG, Dresden), he helped to develop the marine annelid Platynereis dumerilii as a molecular model system (EMBL, Heidelberg). After joining the University of Vienna/Max Perutz Labs as a group leader in 2008, Florian Raible and his team pioneered work on hormones and stem cells in this unique model. Their research has been supported by an ERC starting grant (2010), an FWF Doc.Funds program (SCORPION) focusing on stem cell research (2019) and an FWF special research programme (SFB F78) on the modulation of neuronal stem cells (2019).
Selected Publications
1. Pende M, et al. (2020) A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity. Science Advances 6(22):eaba0365. doi: 10.1126/sciadv.aba0365
2. Andreatta G, et al. (2019) Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis. Proc Natl Acad Sci USA 8:201910262. doi: 10.1073/pnas.1910262116
3. Schenk S, et al. (2019) Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase. Elife 8:161. doi:10.7554/eLife.415562020
4. Schenk S, Krauditsch C, Frühauf P, Gerner C, Raible F (2016) Discovery of methylfarnesoate as the annelid brain hormone reveals an ancient role of sesquiterpenoids in reproduction. Elife 5:e17126. doi:10.7554/eLife.17126
5. Bannister S, et al. (2014) TALENs mediate efficient and heritable mutation of endogenous genes in the marine annelid Platynereis dumerilii. Genetics 197(1):77–89. doi:10.1534/genetics.113.161091