Stem cells are key for the development and maintenance of multicellular organisms. Some animals in addition have remarkable regenerative capacities, which also rely on the activation of stem cells. In this research platform we aim to study the regulation of stem cells during development, regeneration and maintenance in a variety of animals with different life history strategies in order to unravel the mechanisms of regulation that lead to the activation of stem cells. We employ modern single cell technologies in combination with functional genomics approaches.  We also seek to develop new bioinformatic tools for the analysis of single cell transcriptome data.

05.05.2022
 

Nature Communications papers published by Oleg Simakov, Hannah Schmidbaur et al.

31.03.2022
 

Oleg Simakov, Wai Yee Wong, Alena Kizenko et al. published a paper in Frontiers in Genetics

31.03.2022
 

Oleg Simakov, Nicolas Robert et al. published a paper in BMC genomics

15.03.2022
 

Audimax Podcast with Uli Technau

09.03.2022
 

Nature communications paper about evolutionary dynamics of parrot chromosomes by Luohao Xu, Jing Liu, et al.

02.03.2022
 

Cover Story in Journal of Genetics and Genomics