Stem cells are key for the development and maintenance of multicellular organisms. Some animals in addition have remarkable regenerative capacities, which also rely on the activation of stem cells. In this research platform we aim to study the regulation of stem cells during development, regeneration and maintenance in a variety of animals with different life history strategies in order to unravel the mechanisms of regulation that lead to the activation of stem cells. We employ modern single cell technologies in combination with functional genomics approaches.  We also seek to develop new bioinformatic tools for the analysis of single cell transcriptome data.

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20.07.2023
 

iScence paper for Lisa Rouressol et al. (Simakov Group)

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17.05.2023
 

Nature paper for Darrin T. Schultz, Oleg Simakov et al.
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24.01.2023
 

Tetsuo Kon and Koto Kon-Nanjo are first and co-authors in a Communications Biology paper about single-cell transcriptomics of the goldfish retina.
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23.01.2023
 

Oleg Simakov is co-author in a new paper in Genome Research about conserved regulators in the Hydra genome
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18.11.2022
 

Uli Technau et al. published a paper on conservation of transcriptional targets of Brachyury
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13.10.2022
 

Isabell Niedermoser, Tatiana Lebedeva and Grigory Genikhovich have a new Development paper!
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